IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House DOI: 10.7897/2277-4343.100236 IN-VITRO STUDY TO EVALUATE THE COMPARATIVE ANTIMICROBIAL ACTIVITY OF ELA CHOORNA IN AMALAKI SWARASA, KADALI SWARASA AND NARIKELODAKA FOR SELECTED URINARY PATHOGENS Nazneen A. Salam * Priya.S Raiby Paul 11 -0001 53 55 Main objective of the study is to evaluate the comparative antimicrobial activity of Ela (Elettaria cardamomum) choornain amalaki (Embilica officinalis) swarasa, kadali (Musa paradisiaca) swarasa and narikelodaka (Cocos nucifera) in selected UTI pathogens__ampersandsignnbsp;i.e.__ampersandsignnbsp;Escherichia coli,__ampersandsignnbsp;Proteus mirabiliss__ampersandsignnbsp;Klebsiella pneumoniae__ampersandsignnbsp;and__ampersandsignnbsp;Enterobacter aerogenes.__ampersandsignnbsp;In-vitro__ampersandsignnbsp;study was carried out in three methods-Agar Disc diffusion method, Agar well diffusion method and Serial dilution method. To determine the minimum inhibitory concentration (MIC) the agar disc diffusion method is not appropriate, as it is impossible to quantify the amount of antimicrobial agent diffused into the agar medium. So results were not accurate. So other two methods were used. Three drug combinations were tested in increasing concentrations against UTI pathogens. Drug combinations showed zone of inhibition against__ampersandsignnbsp;Klebsiella pneumonia. Among the three combinations of drug tested for antimicrobial activity__ampersandsignnbsp;Ela__ampersandsignnbsp;and__ampersandsignnbsp;Amalaki__ampersandsignnbsp;(40 g__ampersandsignnbsp;Ela__ampersandsignnbsp;in 200 ml__ampersandsignnbsp;amalaki swarasa) combination is more effective against__ampersandsignnbsp;Klebsiella pneumoniain 20 __ampersandsignmicro;l -7.5 mm, 40 __ampersandsignmicro;l 9.5 mm, in 60 __ampersandsignmicro;l 11.7 mm inhibition noted. Serial dilution method was done for confirmation of antimicrobial activity of Ela and amalaki combination against__ampersandsignnbsp;Klebsiella pneumonia.In serial dilution, 30 x 103__ampersandsignnbsp;colonies of__ampersandsignnbsp;Klebsiella pneumonia__ampersandsignnbsp;were reduced to 2 x 102__ampersandsignnbsp;colonies. Mutrakrichra UTI Ela Amalaki Kadali Narikelodaka