IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House DOI: 10.7897/2277-4343.1005105 PHYTO-PHARMACOGNOSTICAL STUDY OF ASTHI SHRINKHALA (CISSUS QUADRANGULARIS LINN.) Rakhi Nautiyal * Suresh Chaubey 11 -0001 54 59 Cissus quadrangularis L. (Asthishrinkhala) belongs to Vitaceae family is an indigenous medicinal plant of India. It is a succulent plant found in warm tropical areas. It has been prescribed in ancient Ayurvedic texts by Bhavaprakash and Chakradutta as a general tonic especially for the fractured patient and also having high therapeutic potential against several diseases. In present study, all aspects about Asthishrinkhala have been taken like name, geographical source, Macroscopic, Microscopic, Physicochemical, Phytochemical (Qualitative and Quantitative) and Chromatographic activities. The macroscopic features of the__ampersandsignnbsp;Cissus quadrangularis__ampersandsignnbsp;L. stem were observed under magnifying lens. The powder microscopy showed the presence of starch grain, calcium oxalate, and fragments of vessels, parenchymatous cells and fibers. The physicochemical properties such as foreign matter, moisture content, ph value, aqueous soluble extract, alcohol soluble extract, petroleum ether soluble extract, total ash, acid insoluble ash, water soluble ash values of stem were carried out. In phytochemical study stem of Asthishrinkhala showed the presence of many important classes of phytoconstituents like carbohydrates, alkaloids, amino acid, protein, saponin, glycosides, phenolic compound, steroids and tannins. Estimation of carotene, total flavonoid content, steroidal content, Vit C, Vit D, calcium and saponins analysis were carried out for quantitative analysis. Cissus quadrangularis Linn. Phytochemical Asthishrinkhala Physicochemical.