IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House DOI: 10.7897/2277-4343.110225 EFFICACY OF SHODHANA AND SHAMANA THERAPY IN MUKHADUSHIKA (ACNE VULGARIS) Ekta Sharma * Pankaj Katara Arun Gupta 11 -0001 27 31 Abstract Acne vulgaris is a chronic disease that occurs in young adults when hair follicles are clogged with dead skin cells and oil from the skin. It is characterized by both inflammatory (papules, pustules and nodules) and non-inflammatory (Comedones, open and closed) lesions. In Ayurvedic classics, in the context of Kshudra Roga, it is mentioned that Mukhadushika occurs in yuvaavastha and its signs and symptoms are similar to that of Acne vulgaris. It is due to vitiation of Vata, Kapha and Rakta having the Shalmali thorn like thick or hard painful eruptions which are impregnated with Meda. The aim is to evaluate the combined efficacy of shodhana and shaman therapy in Mukhadushika (Acne Vulgaris). It is an open randomized clinical trial. A total of 32 patients randomly divided in two groups; Group A - Shodhana (Vamana and Virechana Chikitsa); Group B- Shodhana along with Shamana (Lodhradi lepa and Brihat Manjisthadi kashaya). __ampersandsignlsquo;Wilcoxon matched pairs signed rank test__ampersandsignrsquo; applied for efficacy within the group and __ampersandsignlsquo;Mann-Whitney Test__ampersandsignrsquo; to compare the efficacy of two groups. In Group A, maximum number of patients i.e. 73% showed significant relief, 20% have moderate improvement, 6.7% of patients showed excellent relief; whereas in Group B, 60% of patients showed excellent relief and significant relief was observed in 40% of the patients. Shodhana therapy and Shaman therapy given together have significant effect in the management of Acne Vulgaris as compared to Shodhana therapy alone. Keywords Shodhana Shamana Mukhadushika Acne vulgaris References