IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House DOI: 10.7897/2277-4343.110478 ROLE OF VIRECHANOTTARA SANSHAMANA CHIKITSA IN THE MANAGEMENT OF EKAKUSHTHA (PSORIASIS VULGARIS): A CASE STUDY Niharika Shakya * Govind Kumar Verma Ashutosh Chaturvedi Ritisha Verma Jai Prakash Singh 11 -0001 4 11 Psoriasis is a common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, thickened plaques with overlying silver-white scales. Ekakushtha has signs and symptoms i.e. Aswedanam, Mahavastu and Matsyashakalopamam, which can be compared with symptoms of Psoriasis. Hence it has been taken as analogue to Psoriasis in the present case study. We can compare it with the Ekakushtha in Ayurvedic system of medicine. A case of Ekakushtha (Psoriasis vulgaris) discussed here. A 56 years old male residing in Varanasi visited OPD of Panchakarma, Faculty of Ayurveda, IMS, BHU, Varanasi, presenting with chief complaints as Erythematous scaly itchy lesion over the extensor surface of both the hands and legs, burning sensation at skinny lesion, Dryness at skinny lesion since 3 years diagnosed with Ekakushtha (Psoriasis vulgaris). Patient was successfully treated with Shodhana (Virechana karma) and Shaman Chikitsa. Shamana Chikitsa is carried out by Rasamanikya, Gandhaka Rasayana, Arogyavardhini Vati, Patola Katurohini Kashaya, Pancha Tikta Ghrita Guggulu and Aragwadhadi Lepa. The total duration of the treatment was 6 months, and the Study subject assessed before treatment, after treatment and on follow-up for improvement using PASI scoring and subjective parameter. After course of 6 months treatment provides significant relief in skin lesion, itching, dryness and PASI score. This method of Ayurvedic management for Ekakushtha was found very effective in simple and easiest way. No any adverse effects were observed during treatment, so this therapy is very safe and cost effective. Ekakushtha Psoriasis Vulgaris Virechana Karma Sanshamana Chikitsa Tikta Dravya.