IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House DOI: 10.7897/2277-4343.1104102 COMPARATIVE CLINICAL STUDY OF AYURVEDIC THERAPY AND INTERVENTION IN THE MANAGEMENT OF UTERINE FIBROID: AN OPEN LABEL, PROSPECTIVE RANDOMIZED PARALLEL GROUP STUDY Shivshankar Rajput * Shweta Mata Laxmipriya Dei 11 -0001 128 133 Abstract As the disease uterine fibroid is the most common pelvic benign tumour, modern concepts were illustrated but not in Ayurveda. On the basis of specific clinical features of Mamsaja Arbuda as well as description of Arbuda in general, it can be said that all relatively big neoplasms developing from muscular and fibrous tissues (myoma and fibromas) come under Mamsaja Arbuda. Mainly Kapha-Vata Doshas, vitiate Dhatu particularly Rakta, Mamsa, Meda, also Dhatwagni mandya especially Mamsagni have found to be involved in the pathophysiology of Garbhashaya Arbuda compared with Sanga Pradhana Vyadhi. The present study was carried out to evaluate and compare the effect of Virechana followed by Triphaladi Yoga and Virechana followed by Intra Uterine Uttarbasti along with Triphaladi Yoga on Garbhashaya Arbuda (Uterine fibroid). 77 patients in the age group of 20-50 years were registered for the study, of these patients, 74 were completed the course of treatment. 09.09% patientsOut of 98 fibromyoma, total 19 fibromyoma were completely alleviated. Virechana followed by Triphaladi Yoga showed better results in reducing size and volume of fibroma as well as symptomatic relief i.e. excessive bleeding per vagina during menses, inter menstrual bleeding and irregular menses etc. Keywords Garbhashaya Arbuda Triphaladi Yoga Uterine fibroid Uttarbasti Virechana References