IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House DOI: 10.7897/2277-4343.1105131 EFFECTIVENESS OF KANCHANARA KWATHA IN THE MANAGEMENT OF PRIMARY HYPOTHYROIDISM: CASE SERIES Anju S Lal * Arun Pratap Arjun Chand C.P Miharjan K 11 -0001 9 14 Primary hypothyroidism is a condition that results due to the decreased ability of thyroid gland to produce its hormones Tri-iodothyronine (T3) and Thyroxin (T4) and results in increased TSH production from the Pituitary gland. This decreased hormone secretion may result in reduced metabolism and in Ayurveda, this metabolism may be explained in terms of Dhatu Parinama Siddhanta and this reduced metabolism with Dhatva agnimandya condition. Ten subjects having high TSH levels and one or multiplicity of the symptoms like Lethargy, hairfall, dryness of skin, less appetite, cold intolerance, puffiness of face, hoarseness of voice, muscle aches, menstrual disturbances were selected for the study. They were gradually developing these symptoms since 1 year. They all were given Kanchanara Kwatha 24 ml with 1.5 g Shunthi Choorna as Prakshepaka Dravya twice daily before food for 60 days. Follow up was done on 30th day after the intervention. Assessment of subjects was done by using TSH levels and Zulewski__ampersandsignrsquo;s clinical score for on 0th, 61th and 90th day. The results were analysed statistically. Statistically highly significant result (i.e. p-value = 0.003) were obtained for TSH. When the subjective criteria is analysed, statistically highly significant result (p-value __ampersandsignlt; 0.001) were obtained for the criteria slow movement and statistically significant results (p value __ampersandsignlt; 0.05) were obtained for the criteria__ampersandsignrsquo;s hoarseness of voice, constipation, weight increase, periorbital puffiness. The change obtained for symptoms after the treatment was maintained in the follow-up period too. Above results showed that the drug Kanchanara Kwathais effective in primary hypothyroidism. Primary hypothyroidism Kanchanara Kwatha Thyroid hormones.