IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House DOI: 10.7897/2277-4343.1105150 STANDARDIZATION OF A SIDDHA HERBOMINERAL FORMULATION: KARASOODA SATHU PARPAM P. Sharmila H. Vetha Merlin Kumari * S. Mohan Meenakumari R 11 -0001 103 109 Siddha system is one of the ancient medical systems in India. The siddha is capable of treating all types of disease other than emergency cases. Karasooda Sathu Parpam is a traditional siddha herbomineral drug. The aim of the present study is to investigate the phytochemical, physiochemical and TLC, HPTLC of a traditional Shastric siddha herbomineral formulation known as Karasooda Sathu Parpam. Preliminary phytochemical analysis, HPTLC analysis and physicochemical parameters such as ash values, extractive values and loss of drying were determined as per Pharmacopoeial Laboratory for Indian Medicines (PLIM) guidelines. Phytochemical analysis of different extracts gave positive test for Alkaloids, Flavonoids, Glycosides, Steroids, Triterpenoids, Coumarin, Phenol, Tannins, Saponin, Proteins, Anthocyanin and carbohydrates. HPTLC fingerprint analysis of extracts showed the presence of possible number of components. Physicochemical parameters such as the total ash value was found to be 9.43 __ampersandsignplusmn; 0.19 %, acid insoluble ash value is 0.5133 __ampersandsignplusmn; 0.117% and loss of drying at 105__ampersandsignordm;c is 0.68 __ampersandsignplusmn; 0.10%. The water-soluble extractives and alcohol soluble extractives were found to be 0.4667 __ampersandsignplusmn; 0.22% and 0.2567 __ampersandsignplusmn; 0.086%. Biochemical analysis revealed the presence of Sulphate, Chloride, Carbonate, Iron, Zinc, Calcium, Magnesium, Ammonium, Starch, Alkaloids. Qualitative analysis revealed the presence of Sulphate, Chloride, Carbonate, Aluminum, Iron, Zinc, Calcium, Magnesium, Ammonium, Starch and alkaloids. The study highlights the appropriate application of modern scientific methods for developing the new insights into metal-based Siddha drugs. Karasooda Sathu Parpam Standardization Siddha Herbomineral drug.