IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House DOI: 10.7897/2277-4343.1105170 NEEDLE FREE INJECTION TECHNOLOGY: A REVIEW Geetha Pushpanjali S Leela Praveena V Swamy P V * 11 -0001 205 211 Needleless injection systems are novel ways to introduce various medicines into patients without piercing a conventional needle. Needleless injection technology was developed to reduce the number of needle-stick accidents and associated problems; easy to use, disposable and their use is expected to increase considerably. Self-administration is feasible with these devices. This technology is used to deliver not only drugs but also proteins, peptides, monoclonal antibodies, small molecules and vaccines. This review describes pre-requisites, comparison between hypodermic and needle free injections, manufacturing process, components, types and marketed products. Needle-free injections Needle-free technology Needle-free devices drug administration and drug delivery.