IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House DOI: 10.7897/2277-4343.1106200 A COMPARATIVE STUDY TO EVALUATE THE RUJAHARA (ANALGESIC) EFFECT OF VIRECHANA KARMA AND VAITARANA BASTI IN AMAVATA (RHEUMATOID ARTHRITIS) Divya Gupta * Vishakha R. Wetal Arun Gupta 11 -0001 134 139 In Amavata the most__ampersandsignnbsp;responsible__ampersandsignnbsp;issue__ampersandsignnbsp;Ama is caused__ampersandsignnbsp;because of__ampersandsignnbsp;derangement of__ampersandsignnbsp;Agni particularly__ampersandsignnbsp;Jatharagni. Ama associated with the vitiated Vata Dosha is termed as Amavata. The same__ampersandsignnbsp;disease__ampersandsignnbsp;is mentioned in__ampersandsignnbsp;modern__ampersandsignnbsp;system__ampersandsignnbsp;with the name of__ampersandsignnbsp;Rheumatoid arthritis. In modern Medicine NSAIDs, Glucocorticoids, DMARDs are used. These medicines have many toxic effects like osteoporosis, hypertension, diabetes etc. In present study Virechana Karma and Basti Karma were selected as Shodhana Chikitsa. It is directly mentioned in the Chikitsa Sutra of Amavata by Chakradatta and other texts. The present clinical study was conducted in Patients of age more than 25 year up to 50 year. Patients were randomly divided in two Groups, irrespective of religion, sex, occupation etc. In Group A Virechana was given and Group B Vaitarana basti was given. Group A- There was relief in Sandhishool 21.1%, VAS pain16.1%, Tenderness 23.2 % Swelling 20.7%, DAS 10.8%.,12.1% in ESR. Group B-There was relief in Sandhishool 29.3%, VAS pain 18.2%, Tenderness 37.2 % Swelling 44.9%, DAS28 18%, ESR 23.3%. At follow-up of 30 days Virechana Karma and Vaitarana Basti were almost equally effective to reduce Sandhishool. Vaitarana Basti is significantly effective than Virechana Karma to reduce Tenderness, Swelling. Amavata Rheumatoid arthritis Panchakarma Virechana Basti.