IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.120129 ROLE OF KOSHTHA AND AGNI IN PANCHAKARMA: A CRITICAL REVIEW S Triveni Manju * Vinay Kumar K N 11 -0001 129 132 Ayurveda, the ancient science of life originated in India more than 5,000 years ago and is often called the __ampersandsignldquo;Mother of All Healing__ampersandsignrdquo;. Panchakarma is considered to be the most eminent branch of Ayurveda, as the name suggests it is a __ampersandsignlsquo;five-step__ampersandsignrsquo; process for a complete detoxifying and rejuvenating therapy. Every individual is unique in Prakruti, Dosha, Agni, Koshtha and such other factors. So before administrating any Panchakarma procedure it is must to assess the Agni and Koshtha of the person. Agni and Koshtha role can be explained in 3 aspects- i.e., Poorva Karma (Deepana - Pachana, Snehana and Swedana), Pradhana Karma (Vamana karma, Virechana Karma, Basti Karma and Nasya) and Paschat Karma (Samsarjana krama). An attempt is made in the article to highlight the importance of Agni and Koshtha in all the aspects with respect to Panchakarma. Panchakarma Agni Koshtha Poorvakarma Pradhana Karma Paschat Karma.