IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.130224 A CASE STUDY ON AYURVEDIC MANAGEMENT OF CROHN__ampersandsignrsquo;S DISEASE Laxman C. Lavgankar * Supriya A. Gore 11 -0001 1 6 Introduction- Diseases of the digestive system constitute a significant role in increasing the disease burden in society. Grahani Roga (Disorder of gastro-intestinal tract especially duodenum and lower G.I Tract), according to Ayurveda, is a disease related to gastrointestinal disorders. Observation- A clinically diagnosed male patient with Crohn__ampersandsign#39;s disease 20 years old. The signs and symptoms of Crohn__ampersandsignrsquo;s disease are like the manifestations of Grahani Roga, as explained in Ayurveda texts. Most of the symptoms of Grahani Roga, as mentioned in Ayurveda, resemble Crohn__ampersandsignrsquo;s Disease. These include loss of appetite, fever, weight loss, diarrhea, depression. So, there can be a correlation between the two conditions. To provide practical insights into the therapeutic concepts of Ayurveda, a diagnosed case of Crohn__ampersandsignrsquo;s Disease in a preview of Grahani Roga is discussed in this article. The condition was managed with the help of holistic Herbal and Herbo-mineral compounds mentioned in authentic Ayurveda texts. In this Case Study, treatment given to the patient consisted of a combination of herbs like Kutaj, Bilwa, Darvi, Kamdudha, Vidangadi, Pachak, and Rasasindur with Anupan (co-administer of medicine) of Ghee. Classical Herbo-mineral compounds like Kutajghan vati, Shankh vati, Suwarnmalini Vasant and Panchamrut parpati play an essential role in the treatment plan. According to Ayurveda, it is concluded that there is a correlation between the signs and symptoms of Crohn__ampersandsignrsquo;s Disease and Grahani Roga. Nidan Parivarjana, Pathya- Apathya also play a vital role in Grahani Roga. Grahani Roga Crohn’s Disease Anupan