IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.1305122 A RANDOMIZED CONTROLLED CLINICAL STUDY ON TILA UPANAHA IN THE MANAGEMENT OF SANDHIGATA VATA Dharshana Krishnan O * Praveen BS 11 -0001 53 57 Introduction: Sandhigata vata is one of the vata vyadhi. Snehana and svedana are the commonly prescribed treatments for this. Upanaha sveda is a variety of svedana especially indicated in managing various vata vyadhi with pain and stiffness as presenting symptoms. A previous study on Atasi (Linum usitatissimum) upanaha in managing knee osteoarthritis showed an encouraging outcome. Tila (Sesamum indicum Linn) is a variety of svedopaga dravya, and tila taila (sesamum oil) is considered best in managing vata diseases. Aim: This clinical study will evaluate the efficacy of tila upanaha and atasi upanaha to ascertain the better. Materials and methods: 20 patients fulfilling the diagnostic and inclusion criteria of either sex was selected in each group. Upanaha was done for seven days. Findings were recorded in research performa on the 4th day and 7th day. Follow-up was done on the 15th, 30th, 45th and 60th days. Results: Tila upanaha sveda showed a highly significant (p__ampersandsignlt;0.001) effect on tenderness, womac score, flexion (B/L knees), swelling, and crepitus (Rt knees). Significant (P__ampersandsignlt;0.05) effect on swelling (Lt knee), extension (B/L knee), and insignificant (p__ampersandsigngt;0.05) effect on crepitus (Lt knee). Atasi upanaha sveda showed a highly significant (p__ampersandsignlt;0.001) effect on swelling, tenderness, crepitus, womac score, flexion (B/L knees) and extension (RT knee). Significant (P__ampersandsignlt;0.05) effect on extension (Lt knee). In comparing, a significant difference was seen in swelling of the Rt knee (P__ampersandsignlt;0.05) and Lt knee (p__ampersandsignlt;0.001). Conclusion: Atasi upanaha sveda yielded better relief when compared with tila upanaha sveda in managing sandhigata vata (knee osteoarthritis). Svedana Upanaha Sandhigata Vata Osteoarthritis Tila Atasi