IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.1305127 FORMULATION AND EVALUATION OF TOPICAL GEL OF RUBIA CORDIFOLIA (MANJISTHA) A. Manisha K. Naveen A. Jyothi Padmini Iriventi * 11 -0001 75 79 The objective of the present study was to formulate and evaluate Topical gel containing Manjistha as a drug. A total of six gel formulations were prepared by homogenization technique using stearic acid, cholesterol, tween 80 and chloroform as excipients. Preformulation studies like UV spectrophotometry and FTIR were performed for the drug. Carbopol was used as a gelling agent in the preparation of these gels. Evaluation studies like pH, spreadability, viscosity, homogeneity and in vitro drug release studies were carried out. All the results were obtained to state that prepared gels have shown optimum results. Also, a gel containing stearic acid as a lipid (1:2) has shown maximum drug release compared to other gels. Manjistha Cholesterol Stearic acid Topical gel.