IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.155163 THANGA URAM: A DUAL PERSPECTIVE REVIEW OF ITS PHARMACOLOGICAL BENEFITS IN MODERN AND SIDDHA MEDICINE B Abarna * M Sathyarathish M Natarajan M Raghavi P Shanmugapriya 11 -0001 97 102 The Siddha system of medicine uses mineral and metallic compounds for their high bioavailability and efficacy at low doses. Thanga uram (TU) is one such Siddha Metallo-mineral formulation. A review of the scientific literature on the ingredients of Thanga uram (TU) was undertaken. This wide-ranging assessment involved searching through Siddha literature as well as relevant publications in multiple databases and electronic search engines, including Google scholar, Embase, Mendeley, Pub Med Central, Science Direct, and the National Library of Medicine (NLM). The aim was to gather all pertinent information available on the subject. Thanga uram, with its validated antimicrobial, spermatogenic, cognitive enhancement, and styptic properties, and favourable safety profile, stands as a promising Siddha formulation. Its blend of traditional knowledge and scientific validation underscores its potential in contemporary medicine. The pharmacological actions and organoleptic characteristics of the substance align closely with the indications cited in the literature. This congruence suggests that the substance can be effectively utilized in the treatment of various diseases. Its efficacy is supported by both traditional use and modern scientific validation, making it a promising option for therapeutic applications Thanga uram genito-urinary diseases cognitive enhancement.