IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.16281 A CLINICAL STUDY OF INTRALESIONAL INJECTION OF APAMARGA KSHARA IN MANAGEMENT OF CHARMAKEELA Harshitha M Rao * Sahana Kamath 11 -0001 251 254 Background: Charmakeela is a disease, existing over the ages causing trouble to people. Charmakeela is considered to be a Kshudra roga, caused due to aggravated Vyana Vayu along with Kapha, giving rise to nail-like growth over the Twak (skin). Charmakeela roga can be correlated to Warts by description. Objectives: Clinical evaluation of Effect of Intralesional Injection of Apamarga Kshara in Charmakeela. Method: 30 diagnosed cases of Charmakeela were selected for the study based on inclusion criteria and performed according to proforma designed, in SDM College of Ayurveda, Hospital __ampersandsign Research Centre, Kuthpady, Udupi. In the study, intervention was made on single sitting and observation were carried out for 15 days. Drug: Apamarga Teekshna Pratisaraniya Kshara was prepared according to classical method in the Rasashastra Practical Hall, SDM College of Ayurveda, Hospital __ampersandsign Research Centre, Kuthpady, Udupi. Follow up: on 30th day, after intervention. Result: The study showed effective cure i.e. wart had shed off by 15th day, promising cosmetic result with no recurrence and overcoming existing treatment lacunas. Statistical results showed highly significant. Conclusion: Study showed that Intralesional Injection of Apamarga Kshara is effective in management of Charmakeela. Apamarga Kshara Charmakeela Intralesional Injection Curative Cosmetic value.