IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.163112 UNLOCKING THE MEDICINAL POTENTIAL OF PUNARNAVA: A CONCEPTUAL REVIEW OF BOERHAAVIA DIFFUSA LINN. Abhijeet Kumar Satya Prakash Priyanka Seth Ashwini Kumar Kushwaha * Ambrish Kumar Singh Ajay Kumar 11 -0001 141 145 Punarnava (Boerhaavia diffusa Linn.), a plant belonging to the Nyctaginaceae family, is a significant herb in traditional Ayurvedic medicine. It has been widely used to treat various disorders, with mentions of its therapeutic properties found in the Vedic, Samhita, and Nighantu periods. According to ethno botany, the leaves are eaten as vegetables and the root juice is used to treat rheumatism, asthma, leucorrhoea, encephalitis, and urinary problems. The Punarnava plant has numerous pharmacological activities, including anti-proliferative, immunomodulatory, anti-inflammatory, antitumor, anti-convulsant, hepatoprotective and anti-depressant activities. The plant contains various bioactive compounds, such as alkaloids, glycosides, flavonoids, steroids, and tannins which contribute to its therapeutic properties. This review aims to consolidate existing literature on the properties, pharmacological activities, and medicinal uses of Punarnava, providing insights into its therapeutic potential and scientific validation. Boerhaavia diffusa Punarnava Controversial Status Pharmacological Activities Ethno medical Uses