IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.166208 AYURVEDIC MANAGEMENT OF PROSTATIC HYPERTROPHY (POURISH GRANTHI VIKARA) WITH SIGNIFICANT POST-VOID URINE: A CASE REPORT Pooja Sahu * Shiromani Mishra 11 -0001 33 36 Benign Prostatic Enlargement (BPE), Benign Prostatic Hyperplasia (BPH), and Lower Urinary Tract Symptoms (LUTS) are among the most prevalent disorders affecting elderly men. More than 30% of males above the age of sixty experience moderate to severe LUTS that require medical attention. Although the exact pathogenesis of BPH and BPE remains unclear, the role of the androgen receptor and the androgen system is well established. Prostatic tissue possesses androgen receptors that are activated by the potent androgen dihydrotestosterone (DHT). The enzyme 5__ampersandsignalpha;-reductase, responsible for the conversion of testosterone to DHT, is inhibited by drugs such as finasteride and dutasteride, which help to reduce prostatic growth. In recent years, the significance of metabolic factors and prostatic inflammation in the development and progression of BPE and LUTS has also gained attention. This case study provides a comprehensive understanding of the etiological factors, signs, and symptoms associated with prostatic disorders. The patient received appropriate Ayurvedic treatment for two months, along with regular follow-up assessments. After treatment, there was a significant improvement in the patient’s clinical symptoms and objective findings, as confirmed through ultrasonography (USG), prostate-specific antigen (PSA) levels, and urine flowmetry reports. Although the precise cause of BPH is uncertain, age and hormonal imbalance are recognized as major risk factors. Ayurvedic management offers holistic alternatives such as Vatanulomana Aushadhi, Rasayana (e.g., Shilajit), and Balya Aushadhi, which help to restore systemic balance, nourish body tissues, and promote overall health. These herbal and pharmacological interventions possess potential anti-inflammatory and antioxidant properties that may help to regulate prostatic growth and alleviate associated urinary symptoms. Benign Prostatic Enlargement; Lower Urinary Tract Symptoms; Ayurveda; Rasayana; Vatanulomana Aushadhi.