IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.17264 COMPARATIVE EFFICACY OF PLACEBO VS FENUGREEK SEED EXTRACT MOUTHWASH IN GINGIVITIS SUBJECTS Arati C Koregol Nagaraj B Kalburgi Bilakanti Nikhil* Aditi M Karwir Shruti Hugar 11 -0001 137 142 Gingivitis is the inflammatory condition of gingiva that supports teeth. The consensus is that toxins produced by anaerobic bacteria in oral cavity, specifically those that cause plaque formation, are cause of gingivitis. One spice that can alter texture of food is Trigonella foenum-graecum, commonly known as fenugreek, a member of Fabaceae family. Fenugreek has many well-established pharmacological properties, such as immunomodulatory, antidiabetic, antioxidant, hypocholesterolemic, anti-inflammatory, antiulcerogenic, and antipyretic actions. Objectives: To evaluate clinical parameters at baseline and 21 days post non surgical periodontal therapy after the use of fenugreek seed extract mouthwash and to evaluate the colony count of Porphyromonas gingivalis in plaque samples at baseline and after 21 days the use of fenugreek seed extract mouthwash. Methodology: A total of 30 gingivitis subjects were selected and divided randomly into Group A and B. Group A, non surgical periodontal therapy followed by placebo (15). Group B, non surgical periodontal therapy followed by fenugreek mouthwash (15). The supra gingival plaque samples were collected from both the groups at baseline and 21 days post non surgical periodontal therapy. Results: Significant reduction in clinical parameters and the colony count of Porphyromonas gingivalis after the use of fenugreek mouthwash. Conclusion: Fenugreek seed extract mouthwash has better promising effect on inflammation in gingivitis subjects when compared to gingivitis subjects who had undergone non surgical periodontal therapy alone. Gingivitis Non-surgical periodontal therapy Plaque samples Porphyromonas gingivalis Trigonella foenum-graecum.