IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.173112 A COMPREHENSIVE LITERARY REVIEW OF GARA VISHA IN VANGASENA SAMHITA Sagar Prakash Jalakoti * Chaithra Hebbar Ravikrishna S 11 -0001 141 144 Gara visha is a type of synthetic, compounded poison (samyogaja visha) that is important in the historical and modern settings of food and environmental toxicity. This study offers a thorough literary analysis of the Visharogadhikara Adhyaya, the 75th chapter of the Vangasena Samhita, a 12th-century toxicological treatise by Vangasena. In contrast to acute toxins, Gara visha is described as a combination of several potent secondary poisons that are slow acting (kalantara vipakitvaan) and meant to induce progressive systemic damage or death over an extended period of time. A particular profile of chronic symptoms, including diminished digestive fire (agnimardavam), indigestion, nausea, dyspnea, and overall body weakness, are among the clinical hallmarks of this illness. A multifaceted treatment strategy is provided by the management protocols described in the text, which include direct interventions such as Vrishadi Ghrita, Swarna Prayoga (using gold ash), and Ankota Moola Prayoga. Additionally, the treatise describes a number of broad-spectrum antitoxic compositions that are intended to neutralize many types of inanimate, living, and artificial poisons, including Chandrodaya Agada, Ajeya ghrita, and Mrutyu pashahara ghrita. This analysis connects the ancient Ayurvedic principles with the contemporary need for systemic detoxification solutions by highlighting the Vangasena Samhita__ampersandsign#39;s advanced methodology for identifying and treating chronic, cumulative toxicity. Gara Visha Vangasena Samhita Visharogadhikara Adhyaya