IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.173113 THERAPEUTIC ROLE OF GHRITAS IN THE MANAGEMENT OF PANDU VYADHI: A COMPREHENSIVE REVIEW Seema H. Thakare * Umesh Patil 11 -0001 145 149 Pandu Vyadhi, described in Ayurveda as a Pitta-dominant Tridoshaja disorder, closely resembles the clinical features of anaemia and is primarily associated with impairment of Rasa and Rakta Dhatus. The condition arises due to various dietary, lifestyle, and psychological factors, leading to dosha vikruti, dhatu kshaya, and diminished Agni. If left untreated, it may progress into severe complications such as Kamala and other life-threatening conditions. This review aims to explore the role of Snehapana (internal oleation) and evaluate the therapeutic significance of various medicated ghritas in the management of Pandu Vyadhi. Classical Ayurvedic texts, mainly Charaka Samhita, along with contemporary literature, were systematically reviewed for this purpose. Ghritas hold a central place in Pandu Chikitsa due to their multifaceted properties, including Dosha pacification, Agni deepana, Rasayana effect, and Dhatu poshana. Multiple formulations, such as Dadimadi Ghrita, Mahatiktaka Ghrita, Kalyanaka Ghrita, and Vyoshadi Ghrita, demonstrate targeted therapeutic action based on Dosha predominance and disease pathology. These formulations are used not only as preparatory measures before Shodhana but also as independent therapeutic agents. In conclusion, medicated ghritas represent a versatile and effective modality in the management of Pandu Vyadhi. Their ability to integrate nourishment, detoxification, and disease management highlights their importance in Ayurvedic practice and provides scope for further research and development of integrative therapeutic strategies. Ayurveda Ghrita Pandu Vyadhi Snehapana