IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.173121 A REVIEW ON GOOD MANUFACTURING PRACTICES FOR AYURVEDIC MEDICINES: INTEGRATION OF WHO STANDARDS, INDIAN LAW, AND CLASSICAL CONCEPTS Manish Kumar Saini * Meemansa 11 -0001 182 185 The global use of herbal and Ayurvedic medicines is increasing rapidly; however, the common perception that “natural equals safe” has led to under-regulation and the emergence of avoidable adverse reactions, emphasising the need for stringent Good Manufacturing Practices (GMP). This review aims to present and contextualise GMP requirements for Ayurvedic, Siddha, and Unani (ASU) drugs by integrating World Health Organisation (WHO) guidelines, Indian regulatory provisions, and classical Ayurvedic concepts of standardisation. A review was conducted using WHO documents, the Drugs and Cosmetics Act and Rules (including Schedule T), pharmacognosy literature, and classical Ayurvedic texts such as the Sharangadhara Samhita, focusing on quality assurance, raw material handling, manufacturing infrastructure, documentation, and shelf life. The findings indicate that the GMPs for ASU drugs encompass strict quality control of raw materials, in-process materials, and finished products; defined standards for facilities, hygiene, and personnel; validated manufacturing processes; detailed batch manufacturing and distribution records; and systems for complaint handling and product recall. The classical Ayurvedic literature further provides detailed guidelines on collection time, geographical source, processing methods, equipment, particle size, extraction ratios, and stability, which are closely with modern parameters of identity, purity, potency, and safety. Harmonising WHO recommended GMP frameworks, Indian legal requirements, and traditional Ayurvedic quality principles can significantly improve the safety, efficacy, and global acceptability of ASU drugs, provided these standards are rigorously implemented, monitored, and continuously updated. Good Manufacturing Practices Ayurvedic drugs WHO guidelines Schedule T Sharangadhara Samhita Herbal quality control GACP ASU drug standardisation.