IJRAP International Journal of Research in Ayurveda and Pharmacy 2277-4343 Moksha Publishing House 10.7897/2277-4343.174133 CLINICAL MANAGEMENT OF VATAKUNDALIKA (CHRONIC CYSTITIS) THROUGH MUTRAMARGAGATA UTTARA VASTHI: A CASE REPORT Shweta C. Dindur Gayathry Viswanath * 11 -0001 41 45 Chronic cystitis is an inflammatory condition confined to the urinary bladder. Though its precise prevalence is not well defined, urinary tract infections in Indian women range from 3.14% to 19.87%, indicating the significant burden of this condition. It is characterized by increased urinary frequency, urgency, dysuria and suprapubic pain. In Ayurveda, chronic cystitis can be correlated with Vatakundalika (chronic cystitis), a type of Mutraghata (obstructive urinary disorder) explained by Acharya Susrutha. A 36-year-old female presented to SDM Institute of Ayurveda and Hospital, Bengaluru, with post-void lower abdominal pain of six months’ duration, associated with a history of recurrent urinary tract infection and increased urinary frequency. Pelvic sonography revealed a thickened urinary bladder wall (6.5 mm). In view of the recurrent nature of her complaints and her preference for a more permanent solution, the patient opted for Ayurvedic management. She underwent Mutramargagata Uttara Vasthi (Trans-urethral administration of medicine) as Sthanika Chikitsa (local therapy) during inpatient care, followed by Shamana Aushadhi (oral pacifying medication) after discharge for continued management and prevention of recurrence. Post-treatment, her symptoms resolved completely, and repeat ultrasonography demonstrated a reduction in bladder wall thickness to 5 mm with an insignificant post-void residual urine volume. This case highlights the potential role of Ayurvedic management, particularly Mutramargagata Uttara Vasthi with Vasthyamayanthaka Ghrita (a compound medicated ghee), as an effective, target-specific therapeutic approach for chronic recurrent cystitis. Mutramargagata Uttara Vasthi Chronic Cystitis Detrusor Muscle