Article: A REVIEW ON ACID PEPSIN DISEASES: HISTORY, EPIDEMIOLOGY, ANTACIDS AND PLANT-BASED ALTERNATIVES

Article Category: Review articles

DOI: 10.7897/2277-4343.100356

Pages: 27-32

Author: Anshul *, Alok Srivastava, Gyanendra Datta Sukla

Abstract: Today estimate that about 80% of people in growing nations still believes on traditional medicine based chiefly on species of plants and animals for their basic well-being caution. Herbal medicines are presently in demand and their acceptance is growing day by day. About 500 plants with medicinal use are mentioned in ancient literature and around 800 plants have been used in indigenous systems of medicine. The World Health Assembly (WHA) has acquired several proposals depicting awareness to the aspect that a huge segment of the community in many growing nations still hopes on traditional medicine. Addition of verified traditional medicaments into national drug policies and regulatory measures is proposed. Understanding of their clinical, pharmaceutical and commercial value is still emerging, although this changes extensively between nations^. This manuscript aims at a systematic brief review on few herbal drugs/ dietary nutrients and their extracts having potent action (antiulcerogenic, gastroprotective and anti-inflammatory activity) on gastric disorders and their published data on effectiveness of these diseases. Literature (pharmacological investigations) for concerning medicinal plants and their chemical constituents/extracts were compiled from major databases and academic publishers, such as PubMed, Elsevier, etc. Various numbers of medicinal plants and their extracts are reported to have anti-ulcer activity, gastro-protective activity, and antibacterial activity comparable to the existing treatment (antiulcer and antacids drugs) or sometimes even better in potency. Studies and screening of easily available plants with a well-defined strategy may help to develop effective new drugs or treatment giving permanent relief against acid pepsin disorders without side effect.

Keyword: Acid-pepsin disorders, Traditional medicines, Amlapitta, Gastro-protective.