Article: A CLINICAL STUDY ON EVALUATION OF EFFECT OF KHADIR GHRITA IN EKAKUSHTHA WITH SPECIAL REFERENCE TO PSORIASIS

Article Category: Original Research articles

DOI: 10.7897/2277-4343.1005101

Pages: 31-37

Author: Yogesh Jakhotiya, Vaishali Kuchewar *

Abstract: Psoriasis is an autoimmune, non-contagious, dry, inflammatory skin disorder. Many treatment modalities are available, but chances of recurrence are more and reported to have adverse effects. In Ayurveda, Ekakushtha is described under Kshudra Kushtha which is caused due to vitiation of Vata and kaphadosha (body humors). Khadir is one of the best among Kushthaghna drugs (drugs act on dermatological disorders) and can be used in any form. Cow ghee is having Sanskaranuvartan (characteristic enrichment) property. The objective of this study is to evaluate the efficacy of Khadir ghrita in Ekakushtha. It was a single arm clinical study. Total 30 patients have completed the treatment. First Haritaki powder was given with lukewarm water at bedtime for consecutive three days for koshtha shuddhi (bowel cleaning). Then Khadirghrita 10 ml twice a day with lukewarm water was given in the morning and evening. It was also given for local application in sufficient quantity at night. The duration of medication was 30 days. The main outcome measures are the assessment of patient was done on Day 0, 10, 20, and 30 on the basis of PASI score and gradation of itching. In observation, Psoriasis was predominantly found in males and was in all age groups (20-60 years). Maximum number of patients had chronicity up to 4 years. Significant improvement was found in the erythema, induration and itching. PASI score was also reduced significantly. It can be concluded that oral and local application of Khadirghrita is effective in Ekakushtha.

Keyword: Psoriasis, Ekakushtha, Kshudra Kushtha, Kushthaghna, Khadir ghrita, PASI score