International Journal of Research in Ayurveda and Pharmacy

ISSN Online:2229-3566

ISSN Print: 2277-4343


Article Category: Original Research articles

DOI: 10.7897/2277-4343.1005104

Pages: 49-53

Author: Renu Prasad, Gunjan Sharma, Preeti Singh *, Arun Kumar

Abstract: The present study has been undertaken to demonstrate safety profile for local application of Haritkyadi Lepa (Vidalaka) and Bilwadi kwath for Seka karma in one of the ocular diseases i.e. Shushkakshipaka and to develop the physicochemical profiles of both. Pharmacodynamics of both formulations has been established according to classical texts after their preparations. Organoleptic parameters along with physico-chemical analysis have been also studied. Both samples are also gone through microbiological limit test (MLT) for the estimation of bacterial count. Thin layer chromatography (TLC) of Haritkyadi Lepa as well as of Rasanjana is also studied. Physico-chemical analysis of Haritkyadi lepa reveals pH 5.33, total Ash % 2.1%, water soluble extractive 40.13% and alcohol soluble extractive 11.44% whereas that of Bilwadi kwatha are 3.46, 10.21%, 22.91%, 11.21% respectively. Organoleptic profile of lepa discloses its reddish-brown color, pleasant odor with semi-solid touch and texture while kwatha is a brown colored fine coarse powder with pleasant odor. MLT shows absence of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella species. TLC results shows presence of active compounds. Pharmacodynamics of lepa has dominant properties of kashaya rasa, laghu guna, ushna virya, katu-madhura vipaka and Pitta-kapha dosha shamakta. Bilwadi kwatha has tikta rasa, laghu-ruksha guna, katu vipaka and Vata-kapha dosha shamkta properties. Organoleptic properties indicate safety for local application. MLT determines established specification for microbial quality of both products. Both formulations show magnificent results of physico-chemical analysis which will be advantageous for further researches regarding its efficacy and safety profile.

Keyword: Haritkyadi Lepa, Shushkakshipaka, Bilwadi kwath, Rasanjana.