Article: EVALUATION OF CLINICAL EFFICACY AND SAFETY OF SAINA TABLET IN THE MANAGEMENT OF SINUSITIS (PRATISHAYA)

Article Category: Original Research articles

DOI: 10.7897/2277-4343.1005106

Pages: 60-66

Author: Nimish Vador *, Bhavesh Vador, Charmi Gor, Manali Aalim

Abstract: Sinusitis is one of the most distressing disease conditions affecting the quality related life of individuals, having a recurrent and chronic course with a very poor response to medicines. Though many drugs have been introduced for its management from time to time, complete recovery from the disease is still challenging for the physician. Ayurveda offers large number of single and poly herbal or herbo-mineral drugs for the management of sinusitis (pratishaya) and some of the best of these drugs were selected and saina tablet was formulated. The present trial was carried out to find the efficacy and safety of saina tablets on patients of sinusitis who satisfied the diagnostic and inclusion criteria. Detailed medical history to find out the causative factors like diet and lifestyle and status of disease was recorded and examination of affected areas was done. Patients willing to participate were given saina tablets in the dose of 1 tablet (380 mg each) thrice daily with lukewarm water after meal for the duration of two months with follow up every fifteen days. The primary end points were assessed on basis of improvement in sign and symptoms and quality of life (EQ 5D 5L Questionnaire). Safety assessments were hepatic function [SGPT, SGOT and Alkaline Phosphatase (ALP) and renal function (B. urea and S. Creatinine, Albumin, Globulin)] tests. The finding of the present study suggests that saina tablet is a safe and potential medicine to be used for the treatment of sinusitis.

Keyword: Efficacy and safety, Saina Tablet, Sinusitis.