Article: A PRELIMINARY PHYTOCHEMICAL EXPERIMENTAL STUDY ON GILODYA (CEROPEGIA BULBOSA ROXB. VAR. BULBOSA) WITH SPECIAL REFERENCE TO ITS BALYA KARMA IN MALNOURISHED RATS

Article Category: Original Research articles

DOI: 10.7897/2277-4343.1006121

Pages: 37-41

Author: Meena Manish Kumar *, Jaiswal Mohan Lal

Abstract: In the present day scenario of nutritional crisis, it is the need of the hour to search for new alternate sources to serve as food. Ayurveda have many potential sources described in name of Balya Dravya, one of which is Gilodya Tuber, Tuber of this plant has been used for Balavardhan and nutritional purpose by villagers of Rajasthan (mainly tribal area). The present study was aimed to evaluate the Balya Karma (Strength and Malnutrition) of Powder of Gilodya (Ceropegia bulbosa Roxb. var. bulbosa) (Test drug) in Malnutrition Effect, Weight Loaded Forced Swim Test and Rota Rod Test in experimental animals. Test drug was found safe up to 5000 mg/kg in oral acute dose in rats. In malnutrition model, test drug at dose 540 mg/kg was statistically significant on total protein (0.262 g/dl), haemoglobin (1.01 g/dl), and body weight (14.67 gm) and Standard drug (powder of Bala Root- Sida cordifolia Linn., 270 mg/kg) was found total protein (0.402 g/dl), haemoglobin (1.83 g/dl), and body weight (18.33 gm) but test sample at dose 540 mg was found 3.94 % having lesser response than standard drug. Weight loaded force swim test and Rota Road Test, test drug 540 mg/kg, after comparison with negative control group (group 1), the test drug was found statistically significant and It was 32.35% lesser action in comparison to standard drug (Bala – 270 mg/kg).

Keyword: Gilodya, Balya karma, Experimental Study, Albino Wistar rats