Article: A CLINICAL STUDY ON GRAHANI ROGA AND ITS MANAGEMENT BY AN INDIGENOUS HERBAL COMPOUND

Article Category: Original Research articles

DOI: 10.7897/2277-4343.110110

Pages: 46-51

Author: Aswinee Kumar Sahu *, Dipak Swain, Prasanta Kumar Sahoo, Draupadi Meher

Abstract: Grahani Roga is a disease of Annavaha Srotas caused due to the production of Ama and Mandagni. Elimination of vidagdha paka or apakwa anna through the anal canal is known as Grahani Roga. Acharya Charak has mentioned that Mandagni causes improper digestion of ingested food, which moves either in Urdhwa or Adho-Marga. When it goes into Adho-marga, then it leads to Grahani Gada. Acharya Sushrut has mentioned that, patients of Atisara, during the stage of Agnimandya, if take incompatible diet, may lead to Grahani Roga. So Agni plays an important role for producing this disease. Muhurvaddha muhurdrava mala pravriti (altered bowel habit), Shlesma mala pravriti (mucous in stool) are the main symptoms of this disease. By considering the above facts the trial drug an indigenous herbal compound which contains Bilwa, Chavya, Chitraka and Sunthi in equal quantity was selected to reduce the pathogenesis of this disease. Most of the ingredient of this formulation possesses Ama Pachana, Agni Deepana and Grahi qualities. A total number of 45 patients were selected and divided into two groups. Simple random sampling methods were used in this study. In the study group 30 patients were given with the trial drug and in the other group patients were given with placebo drug. Mild to moderate improvements in symptoms of Grahani found in trial group. In placebo group patients also have shown certain improvement in the symptom of Tikta Amla Udgara and Mukha vairasya. Trial drug has shown more effective in bowel habit of Grahani patients.

Keyword: Grahani Roga, Agni, Ama Dosha, IBS, Ayurveda.