ISSN Print: 2277-4343
Article: A SYSTEMATIC COMPARATIVE QUALITY ASSESSMENT AND STANDARDIZATION OF DASHAN SANSKAR CHURNA: AN AYURVEDIC FORMULATION
Article Category: Original Research articles
Author: Mehul Mehta *, Sushant Sud, Urvi Dave, Vivek Dixit
Abstract: Dashan Sanskar Churna is one of the widely prescribed churna stated in AFI, used in dental problems which are achieved by the abrasive effect of Khatika, whereas the other ingredients concurrently exhibit their particular therapeutic and effects e.g. destruction of bad breath by aromatic ingredients and decolorizing activity by Supari Bhasma. The objective of the study was to put up analytical parameters, along with development of finger printing of Dashan Sanskar Churna and to compare analytical data with that of market samples available. A detailed comparative study of laboratory sample with two market samples has been done conform the same physicochemical parameters along with HPTLC patternfor Quality review and Standardization. Qualitative tests showed the presence of tannins, alkaloids, saponins, glycosides, triterpenoids and calcium. All three samples showed significantly less variations in physicochemical parameters. Colour and percentage of volatile oil was marginally low in the MS-II reflecting the quality of raw materials used. The total tannin in the laboratory prepared sample is 5.60% w/w whereas the findings in market samples were almost half of it i.e. 3% w/w MS-I and 2.64% w/w MS-II. Quantitative estimation of calcium was significantly less as in laboratory sample it was 45% w/w, in MS - I, 41% w/w and in MS - II sample II 43.3% w/w. It can be concluded in case of HPTLC of volatile oil of MS-II no characteristic spots were observed, this may be due to the use of sub-standard quality raw drugs.
Keyword: Dashan Sanskar Churna, Physico-chemical parameters, HPTLC, Standardization