Article: A REVIEW ON PELLETIZATION TECHNIQUES  

Article Category: Review articles

DOI: 10.7897/2277-4343.110376

Pages: 143-147

Author: Dilip M R *, J Joysa Ruby

Abstract: Pelletization is novel drug delivery system which converts fine powder particles into pellets. Pelletization has gained great interest in recent years due to various advantages with respect to conventional dosage form, such as dose uniformity, flexibility in dosage form, prevention of dust formation. This review gives information about advantages, disadvantages, desirable properties of pellets, drug selection criteria and growth mechanism and will provide insight about different methods of pelletization, production process which includes granulation, extrusion and spheronization and drying and also discussed about parameters which influences the quality of the pellets followed by coating of pellets. It also gives brief idea about characterization of pellets like particle size distribution, surface area, shape and sphericity, porosity, density, friability, flow property, disintegration, and dissolution of the pellets are explained with various applications of mentioned techniques.

Keyword: Pellets, Pelletization, Parameters, Coating of pellets, Characterization of pellets, Applications.