Article: A SNAPSHOT ON NANOEMULSIONS FABRICATION TECHNIQUES FOR DRUG DELIVERY SYSTEMS

Article Category: Review articles

DOI: 10.7897/2277-4343.1104115

Pages: 193-200

Author: Manjunath C *, Venkatesh D P, Govinda Reddy Y A

Abstract: Nanoemulsions are budding from conventional emulsion and formation of nanoemulsion is occurred by reducing the interfacial phenomenon to negative and it is a mixture of oil and water which miscible by surfactants and co-surfactants where globule size in the range of 20 – 500 nm and nanoemulsions are the potential pharmaceutical carriers as it can be used for both lipophilic and hydrophilic drugs. Nanoemulsions are getting more attention because they have been shown to be very viable, non-invasive and cost-effective nanocarriers for facilitated transdermal delivery of a wide variety of active ingredients that appear to be highly metabolized or have undesirable side effects when taken orally. Increase in the skin permeation with very low skin irritancy and nanoemulsions are easy to fabricate. This review reveals the fabrication methods and theoretical aspects of nanoemulsion formation, stability problems of nanoemulsions and their prevention methods. Nanoemulsions can be employed to deliver the drug for various drug delivery systems.

Keyword: Nanoemulsion, Fabrication, Assessment, stability.