International Journal of Research in Ayurveda and Pharmacy

ISSN Online:2229-3566

ISSN Print: 2277-4343


Article Category: Original Research articles

DOI: 10.7897/2277-4343.1105139

Pages: 40-45

Author: Kavitha S *, Padmaja V, Jacob M Titus

Abstract: Mukhadushika is one of the skin diseases described under kshudra roga. It is having close resemblance with acne vulgaris. It is the 8th most common disease worldwide. In conventional medicine various topical therapies are available, but long-term use of these drugs observed to have some adverse effects. Owing the gravity of situation, need was felt for search of new safe and effective medicine. So, the formulation Vata pallava malathyadi lepa is selected. Vata pallava malathyadi lepa mentioned in Sharangadhara Samhita consists of six drugs. Research works of single drugs shows anti-bacterial, anti-inflammatory and antioxidant activities. Value addition is a relative proposition assuming magnanimous importance in today’s dynamic world. In general, adding value is the process of changing or transforming a product from its original state to a more valuable state. Value added Vata pallava malathyadi lepa is very convenient and user-friendly dosage form. An effort was made to assess the effect of value-added formulation of vata pallava malathyadi lepa in Mukhadushika. The trial drug was used as an external application. The clinical trial was undertaken as before and after trial with 30 patients for a period of one month and data was collected. Global Acne Grading System (GAGS) is used for the assessment. Grading of pain, swelling, discoloration and oozing before and after treatment were also assessed. The data was tabulated and analyzed using Wilcoxon Signed Rank list. The trial drug showed highly significant effect in reducing acne vulgaris with p value < 0.001.

Keyword: Mukhadushika, kshudra roga, GAGS