Article: ORAL INSULIN DELIVERY: AN OVERVIEW

Article Category: Review articles

DOI: 10.7897/2277-4343.1105165

Pages: 177-184

Author: Swamy P V *, Phanisri D D, Prasanna Rani G

Abstract: Oral insulin is an exciting space of research and development within the field of diabetology. The oral route is taken into account to be the foremost convenient and desired route of drug delivery, particularly, when repeated or routine administration is necessary. Diabetes mellitus is a serious pathologic condition that is to blame for major healthcare problems. Insulin replacement therapy has been employed in the clinical management of diabetes mellitus for over 90 years. So, the development of oral insulin remains an ultimate goal to both enhance ease of use and to produce therapeutic benefits rooted in its direct delivery to the portal vein and liver. This brief review covers the importance, novel approaches of oral insulin delivery as well as challenges, market status and future perspectives of oral insulin products.

Keyword: Oral insulin, insulin replacement therapy, diabetology, diabetes mellitus, hypoglycemia, hyperinsulinemia.