Article: A CRITICAL REVIEW OF JWARAHARA YOGAS OF AYURVEDIC CLASSICS: A PARADIGM TO REVERSE PHARMACOLOGY

Article Category: Review articles

DOI: 10.7897/2277-4343.120120

Pages: 85-95

Author: Hareendran Nair J, Sajna SA, Monisha M, Sandhu G. Joseph, Vijaya R, Aiswarya P, Shan Sasidharan *

Abstract: Jwara is the first and foremost among all somatic diseases. Although an independent disease, it is also seen manifested in the form of premonitory symptom, symptom and causative factor of various disorders. 2019-20 has witnessed a new pandemic identified as Corona virus (COVID-19) with adverse health issues. In proportion to the wide variety of diseases, viral vaccines are very few, that too with adverse effects. Hence there is an urgent need of most promising Indigenous drugs with antipyretic and anti-viral activity in the current scenario. A critical analysis is made to explore the Jwarahara Yogas of classics to unfold the Antiviral, Antipyretic, Antioxidant and Immunomodulatory potential of phytochemicals in formulations. An attempt has been made to explore the antiviral and antipyretic potential of Amrutotharam Kashayam, one of the most popular and widely used Jwarahara yoga in classics. The review will definitely give new insights on the synergistic actions of phytochemicals in formulations to revalidate the clinical evidences and will throw lime light on repurposing of the documented novel drugs and combinations in classics to offer unique preventive strategies and therapeutic solutions to the present pandemic and emerging viral infections.

Keyword: Jwara, Jwarahara Yogas, Antipyretic, Antiviral, Phytochemicals, Formulation.