Article: CHARACTERIZATION OF RASASINDURA: A METALLIC PREPARATION USED IN AYURVEDIC MEDICINE PREPARED BY TWO DIFFERENT METHODS

Article Category: Original Research articles

DOI: 10.7897/2277-4343.13015

Pages: 17-22

Author: R. S. Sawant *, S. S. Savrikar

Abstract: Rasasindura [RS] is a unique mercurial formulation prepared by the Kupi-pakwa Rasayana method, widely used by the physicians of Ayurveda in various diseases. Parada (Mercury) and Gandhaka (Sulphur) are prime ingredients of Rasasindura; however, their proportion varies from formulation to formulation, ranging from 1:1/6 to 1:6. Characterization of the drug helps develop its pharmacopeial standards. An attempt was made to characterize the prepared samples of Samaguna Rasasindura [RSM] & Shadguna Rasasindura [RSD] by X-ray diffraction (XRD) and Field Emission scanning electron microscopy (FESEM), Thermogravimetric Analysis (TGA), Particle size distribution (PSD) with zeta potential & Fourier-transform infrared spectroscopy (FTIR). A significant difference was observed between the pharmacopeial characteristics of Samaguna and Shadaguna balijarita Rasasindura. Variation in the pharmacopeial characteristics is believed to cause the difference in therapeutic actions of two formulations of Rasasindura, which may result from variation in the proportion of ingredients.

Keyword: Ayurvedic Drug, Rasasindura, Kupipakwa Rasayana, Characterization