Article: A CLINICAL STUDY OF ETIOPATHOGENESIS OF OBESE (STHULA) PCOS AND ITS MANAGEMENT BY MEDOHARGUGGULA

Article Category: Original Research articles

DOI: 10.7897/2277-4343.130487

Pages: 52-56

Author: Sonali Sanjay Chaudhari *, Swati S Mohite

Abstract: The polycystic ovarian syndrome is a hormonal disorder affecting 7% of the reproductive age of women. Women with PCOS have an irregular menstrual cycle, excess androgen, anovulation, hirsutism, and infertility. As per Ayurveda, this type of clinical feature is found in Pushpaghni Jataharini and Nashtartava. The present study provides information about some herbal plants, active plant constituents, and some formulations clinically tested in animal models that induce PCOS and humans suffering from PCOS. Aim: A clinical study of etiopathogenesis of obese (Sthula) PCOS and its management by Medoharguggula. Methodology: The two sections have made for a better understanding of the aim and objectives of the present study. The study was conducted on 30 patients. The drug Medoharguggula was given in Vati form with the dosage of 500 mg thrice a day with lukewarm water. This study was conducted at Bharati Ayurveda hospital during 2020-2022. It was a randomized, open clinical trial study. Results: A total of 35 patients were evaluated in this study. Out of which five discontinued the treatment, and 30 patients completed it. Conclusions: The herbal contents of the drug were found effective in reducing weight. It was not found effective in reducing BMI, hirsutism, acanthosis nigricans and weight reduction. Also, the menstrual cycle interval was found to be regular or at the interval of 45 days in 80% of the patients.

Keyword: Polycystic ovarian syndrome, Obesity (Sthaulya), Ayurveda.