Article: PHARMACEUTICAL AND ANALYTICAL STUDY OF SARIVADI VATI: AN HERBOMINERAL FORMULATION FOR KARNA ROGA

Article Category: Original Research articles

DOI: 10.7897/2277-4343.130488

Pages: 57-61

Author: Gunjan Sharma *, Yadevendra Yadav, Priyanka Rani, Arun Kumar, Hemraj Singh Jardhari

Abstract: Shir (head) is known as “Uttamanga” (Best organ) because many specialized sense organs are located. Karna (Ear) is an organ that is termed as “Srotindrya” as it is a specialized organ does work of Sravana (hearing). Pain and severe loss of hearing are found in most ear diseases. Abnormal sounds such as ringing or buzzing in one or both ears that may be regular or irregular may or may not be associated with hearing loss, especially in older adults. This disease is called ‘Karnanada’ and ‘Karnasweda’ in Ayurveda and ‘Taneen wa Dawi’ in the Unani system of medicine. Karnanada (tinnitus) is a disease mentioned under Karnarogas by various Ayurvedic Acharyas (scholars). Karnanada is the commonest Karna (ear) disease, affecting all age groups, especially elder patients. According to Acharya Charaka and Madhava, Karna is one of the Adhisthana of Vata Dosha, and Karnanada is a Vataj Nanatmaja Vyadhi.  Sarivadi vati is the herbo-mineral Ayurvedic formulation mentioned in Bhaishjya Ratnawali in the management of Karnaroga. It was prepared by the classical method mentioned in Bhaisjya Ratnawali, and excipients were added as per the Ayurvedic Pharmacopeia of India. Pharmaceutical analysis of Vati (tablet) preparation was done according to the API and Protocol of drug testing of PLIM. The Pharmaceutical analysis of the tablet shows that it was light brown in colour and average wt. = 567.2 mg, LOD = 2.53, DT=20-21 min, AV=13.44, AIA= 1.91, WSE= 9.52, & ASE=3.54.  The formulation is safe for use, as heavy metals were below the acceptable limit and free from any pathogenic microbes.

Keyword: Karna, Karnanada, Tinnitus Sarivadi Vati, Shalakya Tantra.