Article: A STUDY ON TRENDS IN THE MANAGEMENT OF CHRONIC LIVER DISEASE PATIENTS

Article Category: Original Research articles

DOI: 10.7897/2277-4343.130490

Pages: 66-71

Author: Santanu Mishra *, Mahadevamma L., Bivek Dayal Sah

Abstract: Chronic liver disease (CLD) is a progressive deterioration of liver functions. The generation of clotting factors and other proteins, the detoxification of toxic metabolic products and the excretion of bile are all liver functions. This continuous inflammation, destruction, and regeneration of liver parenchyma led to fibrosis and cirrhosis. These are leading causes of morbidity and mortality in the country, majorly attributed to excessive alcohol consumption, viral hepatitis, or non-alcoholic fatty liver disease. The study aimed to understand the recent trends in managing chronic liver disease. The liver function tests were assessed in all subjects with a history of CLD complications, and treatment was initiated. Patients were re-examined with LFTs to note the efficacy of the treatment. The study showed that CLD is more prevalent in males due to their lifestyle and social habits. The primary drug prescribed was ursodeoxycholic acid (18.7%), with the best advisable diet restrictions of water and salt (17.4%). Follow-up was conducted regarding LFTs and observed improvement with treatment. With the best management plan, liver functioning can be reverted to normal. Management of CLD and its complications is vital to maintaining hepatic function and the quality of life of patients. With a note on progress, the best non-pharmacotherapies can be advised to improve patients’ quality of life. The study provides an idea to physicians regarding the recent trends and ways of planning a therapy.

Keyword: Chronic Liver Disease, Liver Function Tests, Ursodeoxycholic Acid, Management of Liver diseases, Cirrhosis