Article: A STUDY ON ANTIBIOTIC REGIMENS BASED ON CULTURE SENSITIVITY PATTERNS IN URINARY TRACT INFECTION

Article Category: Original Research articles

DOI: 10.7897/2277-4343.130493

Pages: 83-87

Author: Shubha J Kamath *, Mahadevamma L., Shanborlang Rynjah, Aswathy U J

Abstract: Objective: The study aimed to prospectively study the antibiotic regimen used in the urinary tract infection (UTI) post culture sensitivity test and the efficiency of antibiotics. Methods: A total of 113 subjects were enrolled of age above 18 years. The patients with complaints of burning micturition, pyuria, and dysuria were recruited for the study. The suspected patient’s midstream urine samples were collected and analyzed using microbial methods and underwent a culture sensitivity test. Based on the culture report of each patient antibiotic susceptibility pattern was checked. Additionally, various other kidney and blood parameters were noted. Results: We observed that in geriatric patients’ values of Erythrocyte sedimentation rate (ESR), pus cells and clarity of urine were increased due to reduced immune response and co-morbidity. Most of the isolated uro-pathogens like Escherichia coli (47.8%), Klebsiella pneumonia (21.2%), and Pseudomonas aeruginosa (6.2%) showed sensitivity to the carbapenem class of drug-like meropenem, faropenem and resistance towards co-trimoxazole and fluoroquinolone class of antibiotic. A statistically significant difference was observed between the culture organisms and the antibiotics prescribed. Conclusions: The study provided evidence that it is necessary to conduct culture and antibiotic susceptibility tests to start an antibiotic regimen in patients with urinary tract infections. Improper choice of antibiotics may lead to resistance to uro-pathogens, which may even lead to economic burden and decrease the quality of life. 

Keyword: Urinary tract infection, uropathogenic, treatment regimen, culture sensitivity pattern, Resistance