Article: DEVELOPMENT AND EVALUATION OF AN AYURVEDIC HERBAL FORMULATION (MUSA ASAVA) FOR ANTI-UROLITHIATIC ACTIVITY

Article Category: Original Research articles

DOI: 10.7897/2277-4343.140247

Pages: 86-90

Author: Kumanan R *, Faseela Banu PK, Sudev K, Adarsh M, Santhosh C, Siniya TK

Abstract: The present study aims to develop and evaluate a herbal formulation with anti-urolithiatic activity. The study is planned to formulate an ayurvedic preparation (asava) as per official procedures using fresh stem extracts of Musa paradisiaca. The study also evaluates the impact of banana stem contents within the extract and prepared formulation (asava) on dissolving kidney stones for anti-urolithiatic activity. The objective of the current research work was to determine the anti-urolithiatic activity and its toxic element standardization analysis of the Musa paradisiaca. The banana stem asava was evaluated on different parameters like pH, viscosity phytochemical test, TLC, Heavy metal analysis, specific gravity, and organoleptic evaluation along with the fresh stem extract/juice. The phytochemical screening helps to find out the presence of alkaloids, flavonoids, carbohydrates, tannins, proteins, and cellulose. The ICP-MS heavy metal analysis showed the presence of arsenic and mercury. The anti-urolithiatic activity result indicated a 10% and 33% decrease in the stone weight in the presence of raw juice and Musa asava, respectively. Thus, it shows that regular Musa asava can reduce the chances of kidney stone formation.

Keyword: Anti-urolithiatic, Musa asava, ICP-MS analysis