International Journal of Research in Ayurveda and Pharmacy

ISSN Online:2229-3566

ISSN Print: 2277-4343


Article Category: Original Research articles

DOI: 10.7897/2277-4343.1405139

Pages: 22-26

Author: Shamshalniha S *, Anbu N

Abstract: Aim: The aim of the study was to analyze the chemical contaminants such as heavy metals, aflatoxins and pesticide residues in Siddha polyherbal formulation Sevviyadhi Chooranam, in powder form is indicated for the treatment and management of Sinusitis. Materials and Methods: Sevviyadhi Chooranam, the Siddha polyherbal formulation was prepared as per GMP (Good Manufacturing Practices) guidelines. The formulation was analyzed for heavy metals such as mercury, arsenic, lead and cadmium, aflatoxins such as aflatoxin B1, B2, G1, G2 and pesticide residues such as organochlorine pesticides, organophosphorus pesticides, organo carbamates and pyrethroids at Noble Research Solutions, Kolathur, Chennai. Results: Heavy Metal analysis of SC showed that the presence of Lead about 0.26PPM, Arsenic about 0.61 PPM, Mercury and Cadmium in below detection level. Aflatoxin assay of SC resulted absence of Aflatoxin B1, B2, G1 and G2. Pesticide residue analysis revealed the absence of organochloride pesticides, organophosphorus pesticides, organo carbamates and pyrethroids. Conclusion: The findings of this study revealed the presence of heavy metals such as lead and arsenic in limited amount and absence of mercury and cadmium, and absence of aflatoxins and pesticide residue in the Siddha polyherbal formulation Sevviyadhi chooranam. The study ensured that Sevviyadhi chooranam was free from chemical contaminants such as heavy metals, aflatoxins and pesticide residue and validated the safety of SC for therapeutic usage in treatment of sinusitis.

Keyword: Siddha medicine, Sevviyadhi Chooranam, Sinusitis, Chemical contaminants, Heavy metals analysis, Aflatoxin assay, Pesticide residues