Article: EVALUATION OF THE HAEMOSTATIC EFFECT OF PANCHAVALKALA KASHAYA AND AQUEOUS EXTRACT IN WISTAR RATS

Article Category: Original Research articles

DOI: 10.7897/2277-4343.15245

Pages: 83-86

Author: Aiswarya Rose *, Sreejith Satheesan

Abstract: The effect of Panchavalkala group of drugs on blood coagulation has not been scientifically tested despite it has mentioned in Ayurveda by Acharya Sushruta. The current study investigates the effect of Panchavalkala kashaya and Panchavalkala aqueous extracts on Wistar rats by tail tip amputation method. Amount of bleeding and Haemostatic time is observed immediately after tail tip amputation in heparinised and non- heparinised groups. The data was analysed using Kruskal Wallis test. In non-heparinized category of Wistar rats proved that both Panchavalkala kashaya and Panchavalkala aqueous extract have highly significant haemostatic effect in the test animals. Panchavalkala aqueous extract was more effective in reducing haemostatic time as well as the amount of bleeding in heparinised Wistar rats when compared to Panchavalkala kashaya, which did not show any significant haemostatic effect in the heparinized test animals.

Keyword: Haemostatic, Panchavalkala kashaya, Panchavalkala aqueous extract.