Article: COMPARISON OF SELECTED BIOCHEMICAL PARAMETERS OF ATTENTION DEFICIT HYPERACTIVITY DISORDER CHILDREN AND NORMAL CHILDREN

Article Category: Original Research articles

DOI: 10.7897/2277-4343.15382

Pages: 119-123

Author: E. Srignanasoundari *, Satheesh Kumar C

Abstract: ADHD is one of the most commonly diagnosed behavioural disorders of children, and it occurs in approximately 6-9 % of school-aged children. This study aimed to compare the selected biochemical parameters in blood plasma of Attention Deficit Hyperactivity Disorder (ADHD) children and normal children. A prospective study was conducted on ADHD children at Adhiparasakthi Annai Illam, Melmaruvathur, Kancheepuram district, Tamil Nadu, India, and normal children at Sothupakkam Secondary School, Melmaruvathur, Kancheepuram district, Tamil Nadu, India. After the written consent from the parents and head of the institution, a biochemical examination of the serum ferritin and serum zinc levels was performed. A total of 20 children between 6-12 years had been selected. Results reported that the mean serum ferritin levels of normal and ADHD boys were 22.94 and 13.17, respectively, and the mean serum ferritin levels of normal and ADHD girls were 18.53 and 8.93, respectively. The mean serum zinc levels of normal and ADHD boys were 87.89 and 30.99, respectively, and the mean serum zinc levels of normal and ADHD girls were 69.33 and 30.33, respectively. The study concludes that there might be a positive correlation between blood level of serum ferritin and serum zinc among ADHD children r = 0.632, p = 0.050. There was no correlation between blood level of serum ferritin and serum zinc among normal children r = -0.384, p = 0.274. The study suggested that serum iron and serum zinc levels among ADHD children were very low compared to normal children.

Keyword: Attention Deficit Hyperactivity Disorder, comparison, biochemical parameters, serum ferritin and serum zinc