Article: EVALUATION OF THE CLINICAL EFFICACY OF ZANTHOXYLUM RHETSA (ROXB.) DC. IN SIRAJA GRANTHI (VARICOSE VEIN)

Article Category: Original Research articles

DOI: 10.7897/2277-4343.16116

Pages: 90-95

Author: Veena Naik, Subrahmanya P *, Gajanana Hegade

Abstract: Ayurveda is a science describes about many diseases condition with appropriate manifold therapeutic conditions. Siraja granthi (Varicose vein) is a disease, where due to exertion, vata increases and cause pain , squeezing, dilatation of veins mostly seen in the lower limbs. The folklore practitioners of Dakshina Kannada district are successfully using the Zanthoxylum rhetsa (Roxb.) DC. bark powder mixed with lemon juice as external application in case of varicose veins. Objectives- To evaluate the clinical efficacy of Zanthoxylum rhetsa (Roxb.) DC. in Siraja granthi. Methodology- Single blind clinical study with 2 Groups, 100 patients in each group, Group A is with Zanthoxylum rhetsa (Roxb.) DC bark kwatha internally and external application of Zanthoxylum rhetsa (Roxb.) DC with lemon juice, where as in Group B only Zanthoxylum rhetsa (Roxb.) DC external application with lemon juice, was given, intervention period was for 14 days and follow up on 28^th day and 42^nd day. Observation- Subjective and objective parameters were assessed using grading criteria on the 7th, 14th, 28th, and 42nd days. The collected data was then analysed statistically. Results- It has been proved with good effect. Conclusion- The subjective parameters, Shoola (pain), Kandu (itching), and Daha (burning sensation) showed significant reduction. The objective parameters, including Shotha (swelling), tortuosity, and skin changes, exhibited moderate improvement.

Keyword: Zanthoxylum rhetsa (ROXB.) DC. Siraja granthi, Varicose vein, clinical study.