Article: ROLE OF TRADITIONAL INDIAN MEDICINE AND INTERVENTIONS IN DYSBIOSIS MANAGEMENT AND PERSONALIZED GUT MICROBIOME INTERPLAY: A REVIEW

Article Category: Review articles

DOI: 10.7897/2277-4343.16272

Pages: 199-208

Author: Poona Nath Chouhan *, Sapna Thakur

Abstract: The human gut microbiota, an intricate community of trillions of microorganisms, is essential to human health, influencing digestion, immunity, and neurochemistry. Dysbiosis, or imbalances within this ecosystem, has been linked to conditions such as obesity, diabetes, inflammatory diseases, and mental health disorders. Ayurveda medicine offers an array of therapies aimed at maintaining gut health through personalized dietary guidelines, herbal formulations, and detoxification techniques. This review evaluates the mechanisms by which specific Ayurvedic drugs and interventions particularly Triphala, Guduchi, Ashwagandha and Vaman (therapeutic emesis), Virechana (therapeutic purgation) and Basti karma (therapeutic enema) therapy modulate gut microbiota composition and functionality, potentially offering new therapeutic pathways for gut-related and metabolic disorders. The review synthesizes Ayurvedic principles with modern microbiome research, proposing that Ayurvedic practices could play a vital role in microbiome management. These practices collectively highlight Ayurveda's potential to address dysbiosis and its associated health conditions by targeting specific aspects of microbial diversity and functionality. By integrating ancient Ayurvedic wisdom with contemporary scientific findings, this review explores Ayurveda’s contribution to personalized healthcare, emphasizing its potential to support metabolic, immune, and inflammatory health. This integrative approach offers a promising avenue for developing microbiome-targeted therapies that address preventive and therapeutic needs, aligning with the growing interest in personalized and holistic strategies.

Keyword: Ayurveda, Dysbiosis, Gut-microbiome, Triphala, Herbal, Guduchi, Turmeric