Article: KOSHAMRA (SCHLEICHERA OLEOSA (LOUR.) OKEN): AN INTEGRATIVE REVIEW OF ITS AYURVEDIC, PHYTOCHEMICAL, PHARMACOLOGICAL AND ETHNOMEDICINAL INSIGHTS

Article Category: Review articles

DOI: 10.7897/2277-4343.166221

Pages: 104-109

Author: Jain Aakriti *, N. Aiswarya, Xalxo R. Anjana, Sahu Subash

Abstract: Schleichera oleosa (Lour.) Oken, known as Koshamra, is a medium-sized tree belonging to the family Sapindaceae and traditionally has been used in Ayurveda for its therapeutic benefits. The different parts of the plant are used in the management of various ailments like skin diseases, diarrhea, rheumatism, wound healing and hair related conditions. The objective of the present review is to analyse the phytochemical profile, pharmacological properties, ethnomedicine and safety profile of the plant. A comprehensive review of classical Ayurvedic text, electronic databases such as PubMed, Web of science, Scopus was conducted. The phytochemical investigations have identified the various bioactive compounds such as quercetin, lupeol, stigmasterol, betulinic acid, triterpenoids, taraxerone which contribute to a broad spectrum of activities, including antioxidant, anti-inflammatory, anti-microbial, antidiabetic, anti-cancer and hepatoprotective activities. The pharmacological studies support the traditional uses, but comprehensive clinical validations remain limited. The research further should be done to elucidate the mechanism of action, standardized doses and assess potential toxicological risks. The limited research and its underutilization pave a need to increase its awareness and propagate its ethnomedicinal significance. Thus, Schleichera oleosa (Lour.) Oken holds a significant source of novel therapeutic agents and further research on standardization, clinical evaluation should be undertaken.

Keyword: Schleichera oleosa (Lour.) Oken, Koshamra, Ayurveda, Ethnomedicine, Phytochemical