Article: INTEGRATIVE MECHANISMS OF AYURVEDIC ADAPTOGENS IN STRESS REGULATION AND COGNITIVE ENHANCEMENT: A REVIEW

Article Category: Review articles

DOI: 10.7897/2277-4343.166230

Pages: 148-152

Author: Anjali Sudhakar *, Aswathy L

Abstract: Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and high cortisol levels can cause diffuse inflammation, oxidative damage, and neurodegenerative mechanisms, making stress and cognitive impairment major problems in today’s world. This review aims to look into the role of Ayurvedic adaptogens in stress reduction and cognitive improvement, with a focus on their pharmacological mechanism of action, therapeutic benefits, and consistency with current scientific knowledge. Information on adaptogens, their effect on HPA axis, cortisol management, neuroplasticity, and oxidative stress was gathered from clinical studies, traditional Ayurvedic literature, and contemporary scientific publications. Ayurvedic adaptogens have a significant effect in promoting Sattva guna (mental clarity), supporting Dhatus, and balancing Doshas. These herbs improve neuroplasticity, lower cortisol levels, control HPA axis and reduce inflammation and oxidative stress. Their ability to reduce anxiety, improve memory and concentration, and restore physiological and psychological balance is proven by clinical studies. Also, it presents a comprehensive knowledge of these medicines by merging modern scientific research with traditional Ayurvedic principles like Ojas and Medhya Rasayana. Ayurvedic adaptogens can be a holistic approach to stress management and cognitive impairment when used along with modern therapy. When used with other techniques like yoga and pranayama, these adaptogens can be a complete approach to mental clarity, resilience and overall well-being. To fully understand their role in integrative medicine, more research is needed on their safety profiles and mechanisms.

Keyword: Ayurveda, adaptogens, stress, mental health