Article: A REVIEW ON PHARMACODYNAMICS OF LAXMIVILAS RASA (NARDIYA) WITH SPECIAL REFERENCE TO ALLERGIC RHINITIS

Article Category: Review articles

DOI: 10.7897/2277-4343.17286

Pages: 236-243

Author: Sani Mol Sunny *, Pronab Haldar, Akhilesh Shrivastava

Abstract: Allergic Rhinitis is an immunological inflammatory response of the nasal mucosa to airborne allergens. Although Allergic Rhinitis is not a life-threatening disease, the symptoms of Allergic Rhinitis can affect the overall quality of life. Allergic Rhinitis is characterized by watery nasal discharge, nasal obstruction, nasal mucosal pallor, sneezing, and itching in the eyes, palate, and pharynx. Pratishyaya (rhinitis/nasal disorder) is a broad term mentioned in Ayurveda in which many types of rhinitis are covered. Characteristically, Pratishyaya (rhinitis) is the disease in which kapha (mucus-related bodily humor) and other dosha (functional bio-elements: vata, pitta, kapha) get dragged towards vayu (principle of movement/air) and are expelled out through the nostrils. Rasaushadhies (herbo-mineral Ayurvedic formulations) are considered highly effective even in minute doses and act quickly at the target site. Laxmivilas Rasa (nardiya) (classical herbo-mineral formulation) is a time-tested formulation widely used by ayurvedic practitioners for correcting this disease. This formulation is mainly indicated in the management of specific disease conditions originating from vata (movement-regulating principle) and kapha (structure and lubrication principle) dosha (bio-regulatory factors). The modern scientific era requires explanations and logic behind the mode of action of various ayurvedic treatments. Hence, this review is an attempt to explain the mode of action (pharmacodynamics) of this formulation. Since analysis of the mode of action provides deep insight into the usage of formulations with a better understanding. This helps physician to use the medicine in contexts other than those traditionally indicated.

Keyword: Rasaushadhies (herbo-mineral formulations), Pharmacological, Pharmacodynamics, Pratishyaya (rhinitis), Laxmivilas Rasa (classical formulation).